Key publications

Zhu H*, Wang G* , Nguyen-Ngoc KV, Kim D, Miller M, Goss G, Kovsky J, Harrington AR, Saunders DC, Hopkirk AL, Melton R, Powers AC, Preissl S, Spagnoli FM, Gaulton KJ, Sander M. Understanding cell fate acquisition in stem-cell-derived pancreatic islets using single-cell multiome-inferred regulomes. Dev Cell. 2023 May 8;58(9):727-743.e11. doi: 10.1016/j.devcel.2023.03.011. Epub 2023 Apr 10. PubMed PMID: 37040771; PubMed Central PMCID: PMC10175223.

Benaglio P*, Zhu H*, Okino ML*, Yan J, Elgamal R, Nariai N, Beebe E, Korgaonkar K, Qiu Y, Donovan MKR, Chiou J, Wang G, Newsome J, Kaur J, Miller M, Preissl S, Corban S, Aylward A, Taipale J, Ren B, Frazer KA, Sander M, Gaulton KJ. Type 1 diabetes risk genes mediate pancreatic beta cell survival in response to proinflammatory cytokines. Cell Genom. 2022 Dec 14;2(12):100214. doi: 10.1016/j.xgen.2022.100214. eCollection 2022 Dec 14. PubMed PMID: 36778047; PubMed Central PMCID: PMC9903835.

Other publications

Jun Y, Nguyen-Ngoc KV, Sai S, Bender RHF, Gong W, Kravets V, Zhu H, Hatch CJ, Schlichting M, Gaetani R, Mallick M, Hachey SJ, Christman KL, George SC, Hughes CCW, Sander M. Engineered vasculature induces functional maturation of pluripotent stem cell-derived islet organoids. Dev Cell. 2025 Sep 22;60(18):2455-2469.e7. doi: 10.1016/j.devcel.2025.04.024. Epub 2025 May 23. PMID: 40412386; PMCID: PMC12353569.

Ramms B, Pollow DP, Zhu H, Nora C, Harrington AR, Omar I, Gordts PLSM, Wortham M, Sander M. Systemic LSD1 Inhibition Prevents Aberrant Remodeling of Metabolism in Obesity. Diabetes. 2022 Dec 1;71(12):2513-2529. doi: 10.2337/db21-1131. PubMed PMID: 36162056; PubMed Central PMCID: PMC9750949.

Nguyen-Ngoc K, Jun Y, Sai S, Bender R, Kravets V, Zhu H, Hatch C, Schlichting M, Gaetani R, Mallick M, Hachey S, Christman K, George S, Hughes C, Sander M. Engineered vasculature induces functional maturation of pluripotent stem cell-derived islet organoids. [preprint]. bioRxiv. 2022 October. doi: 10.1101/2022.10.28.513298.

Fung CW*, Zhou S*, Zhu H*, Wei X, Wu Z, Wu AR. Cell fate determining molecular switches and signaling pathways in Pax7-expressing somitic mesoderm. Cell Discov. 2022 Jun 28;8(1):61. doi: 10.1038/s41421-022-00407-0. PubMed PMID: 35764624; PubMed Central PMCID: PMC9240041.

Zhou Z, Gong M, Pande A, Lisewski U, Röpke T, Purfürst B, liang L, Jia S, Frühler S, Margineanu A, Zeng C, Zhu H, Kühnen P, Khodaverdi S, Krill W, Chen W, Sander M, Raile K, Izsvak Z. A missense KCNQ1 Mutation Impairs Insulin Secretion in Neonatal Diabetes. [preprint]. bioRxiv. 2021 August. doi: 10.1101/2021.08.24.457485.

Zhou S, Han L, Weng M, Zhu H, Heng Y, Wang G, Shen Z, Chen X, Fu X, Zhang M, Wu Z. Paxbp1 controls a key checkpoint for cell growth and survival during early activation of quiescent muscle satellite cells. Proc Natl Acad Sci USA. 2021 Mar 30;118(13). doi: 10.1073/pnas.2021093118. PubMed PMID: 33753492; PubMed Central PMCID: PMC8020634.

Wang G, Zhu H, Situ C, Han L, Yu Y, Cheung TH, Liu K, Wu Z. p110α of PI3K is necessary and sufficient for quiescence exit in adult muscle satellite cells. EMBO J. 2018 Apr 13;37(8). doi: 10.15252/embj.201798239. Epub 2018 Mar 26. PubMed PMID: 29581096; PubMed Central PMCID: PMC5897777.

Zhu H*, Xiao F*, Wang G, Wei X, Jiang L, Chen Y, Zhu L, Wang H, Diao Y, Wang H, Ip NY, Cheung TH, Wu Z. STAT3 Regulates Self-Renewal of Adult Muscle Satellite Cells during Injury-Induced Muscle Regeneration. Cell Rep. 2016 Aug 23;16(8):2102-2115. doi: 10.1016/j.celrep.2016.07.041. Epub 2016 Aug 11. PubMed PMID: 27524611.

Diao Y, Guo X, Li Y, Sun K, Lu L, Jiang L, Fu X, Zhu H, Sun H, Wang H, Wu Z. Pax3/7BP is a Pax7- and Pax3-binding protein that regulates the proliferation of muscle precursor cells by an epigenetic mechanism. Cell Stem Cell. 2012 Aug 3;11(2):231-41. doi: 10.1016/j.stem.2012.05.022. PubMed PMID: 22862948.

First/Co-first author papers (* equal contribution)